Lymphatic vessels beat faster as they fill with fluid through a chain of calcium signaling, though the first pressure sensor ...

Diverse combinations of glutamate receptor subunits are expressed across developmental stages and even between adjacent ...

Learn more about eLife assessments The distribution of synaptic and extra-synaptic AMPA receptors (AMPARs) on neuronal plasma membranes is correlated with learning and memory. Although AMPAR ...

In the presence of emulated cone loss, eye movements are used to gather and integrate information, leading to improved letter ...

Recording the spiking activity of muscle fibers at high resolution in awake, behaving mice, reveals that locomotor speed is driven by highly variable subsets of motor units.

Department of Molecular, Cellular, and Developmental Biology, The University of Toledo, United States; Department of Neurosciences and Psychiatry, The University of Toledo, United States; ...

eLife reviews research in which approaches from the physical sciences are used to provide insights into the properties of biological systems and processes. Learn more about what we review and sign up ...

The steroid hormone dafachronic acid may carry the effects of reduced mTOR activity between tissues to coordinate metabolism and longevity across the body.

Cryo-electron tomography uncovers the flexible, filamentous architecture of mouse ciliary rootlets and their regular cross-striations with extensive membrane connections.

2025 marked the third year of eLife’s publish-review-curate model as a way to show how research publishing and assessment can be done differently. Highlights from the year included announcing our new ...

What do the British Psychology Society, the journal Functional Ecology and an astronomy website called Astrobites have in common? The answer is that they all attempt to explain the findings of ...

How proteins control the biogenesis of cellular lipid droplets (LDs) is poorly understood. Using Drosophila and human cells, we show here that seipin, an ER protein implicated in LD biology, mediates ...