British Journal of Ophthalmology

Light-at-night and short sleep: a synergistic dual threat to myopia in children and adolescents

Purpose To determine the independent and joint effects of nighttime light exposure and sleep duration on childhood myopia and ...
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Comparative recurrence rates of varicella zoster virus and herpes simplex virus keratitis

Purpose To compare the recurrence rates of herpes simplex virus type 1 (HSV-1) keratitis (HSK) and varicella zoster virus (VZV) keratitis (VZK). Methods This was a cohort study of patients attending ...
British Journal of Ophthalmology

Axial elongation is associated with stress-dominant aqueous humour proteomic changes in eyes with and without open-angle glaucoma

Background/aims Axial elongation is associated with increased susceptibility to ocular disease, including glaucoma yet the ...
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Effect of laser peripheral iridotomy location on angle widening in primary angle closure suspects: the six-year ZAP trial

3 State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University; Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science; Guangdong Provincial Clinical ...
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Ellipsoid zone defects in age-related macular degeneration: the Beijing Eye Study

Purpose To assess prevalence and associations of ellipsoid zone (EZ) defects on optical coherence tomographic (OCT) images in a general population affected by age-related macular degeneration (AMD) or ...
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Intra-arterial melphalan for the treatment of high-grade uveal lymphoma

High-grade lymphoma with uveal involvement is a rare cancer with poor visual and survival prognosis. We describe our experience using intra-arterial melphalan to treat four eyes of three patients with ...
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Application of the digital flicker test in optic neuritis and optic neuropathies of different aetiologies

Background Eyes with acute optic neuritis (ON) perceive a flickering field at medium frequencies as darker than a steady one (darkness enhancement (DE)), which may be examined by the digital flicker ...
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Can hyperbaric oxygen therapy revolutionise the management of central retinal artery occlusion? A systematic review and meta-analysis of its efficacy and safety

Introduction Central retinal artery occlusion (CRAO) is a vision-threatening ophthalmic emergency with limited proven treatment options. Hyperbaric oxygen therapy (HBOT) may improve inner retinal ...
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Retinal nerve fibre layer thickness change in the parapapillary region

Purpose To assess radial changes in the retinal nerve fibre layer thickness (RNFLT) in the temporal parapapillary region. Methods Using radial optical coherence tomographic images of the optic nerve ...
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Statin use is associated with lower risk of open-angle glaucoma incidence and treatment escalation

Background Retrospective cohort study using the TriNetX database to explore the relationship between statin use and glaucoma. Methods The open-angle glaucoma (OAG) incidence analysis consisted of ...
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MiKid-QA: construction and performance evaluation of a paediatric myopia education question-answering model

Background The surging prevalence of paediatric myopia has overwhelmed clinical education services. While general-purpose large language models (LLMs) are increasingly used for medical information, ...
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Association between varicose veins and central serous chorioretinopathy

To investigate the association between varicose veins and central serous chorioretinopathy (CSCR), based on emerging genetic evidence of a shared vascular mechanism. Methods Propensity score-matched ...