The human genome is no longer just a sequence to be read. It’s a dynamic structure that twists, folds, and reshapes itself in ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

For decades, geneticists have known that most common illnesses are not caused by a single rogue gene but by intricate ...

Researchers at Duke University used CRISPR technologies to discover previously unannotated stretches of DNA in the ‘dark genome’ that are responsible for controlling how cells sense and respond to the ...

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

One of the biggest quests in biology is understanding how every cell in an animal's body carries an identical genome yet ...

A new genome-wide mapping method finally shows how thousands of genes connect to drive disease. Biomedical researchers are working intensively to identify the genes that contribute to disease, with ...