Peptides from the N-heptad repeat region of the HIV gp41 protein can inhibit viral fusion, but their potency is limited by a low tendency to form a trimeric coiled-coil. Accordingly, stabilization of ...
The amino acid sequence of parallel left-handed coiled-coils shows a characteristic seven-residue periodicity with apolar residues in the first and fourth position. The resulting hydrophobic stripe ...
Hv1/VSOP is a dimeric voltage-gated H + channel in which the gating of one subunit is reportedly coupled to that of the other subunit within the dimer. The molecular basis for dimer formation and ...
Scientists at the University of Birmingham have developed a new class of MRI contrast agents: improving their stability to create a significant advancement in medical imaging technology. Metallo ...
New class of highly stable, protein-inspired MRI contrast agents has the potential to revolutionise medical imaging. November 10, 2025: Scientists at the University of Birmingham have developed a new ...
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