The surfaces of Gram-negative bacteria are adorned with versatile nanomachines that include Type IV pili and associated secretion systems. These structures are crucial for a range of functions such as ...

Protein production is a multi-billion dollar industry, with applications in pharmaceuticals, industrial enzyme use (eg in laundry detergent), and biomaterials. Bacteria are receiving renewed interest ...

Type 3 secretion systems (T3SSs) are used by several pathogenic bacterial species to deliver effector proteins, responsible for the effects of infection, into the target host cells. An MGH research ...

With antibiotic-resistant bacteria on the rise, scientists have been searching for ways to shut down the Type IV secretion system (T4SS), a protein complex on the outer envelope of bacterial cells ...

With antibiotic-resistant bacteria on the rise, scientists have been searching for ways to shut down the Type IV secretion system (T4SS), a protein complex on the outer envelope of bacterial cells ...

Bacteria have complex molecular machines that help them drive disease. Scientists can now leverage these machines to treat disease instead. It is nice to deliver drugs where you exactly want them, ...

Researchers at Umeå University in Sweden published a study “Breaking barriers: pCF10 type 4 secretion system relies on a self-regulating muramidase to modulate the cell wall” in mBIO that describes ...

Pseudomonas bacteria can defend themselves against attacks from other bacteria, but this makes them more sensitive to antibiotics.

You suddenly feel sick -- pathogenic bacteria have managed to colonize and spread in your body! The weapons they use for their invasion are harmful toxins that target the host's defense mechanisms and ...

Postdoctoral research associate Samuel Eastman (left), 2024 Princeton graduate Kaeli Ficco (right), and their colleagues uncovered a mechanism by which soil bacteria can modulate plant immunity. To ...