Figure 1: Design of double-cysteine mutants of the 380-kDa dynein motor domain for disulfide cross-linking between the two helices of the stalk coiled coil. These studies, especially the helix-sliding ...

Protein scaffolds can provide a promising alternative to antibodies for various biomedical and biotechnological applications, including therapeutics. Here we describe the design and development of the ...

Gram-negative phytopathogenic bacteria translocate effector proteins into plant cells to subvert host defenses. These effectors can be recognized by plant nucleotide-binding–leucine-rich repeat immune ...

Try this speculation on for size: Maybe the reason more functional partners for amyloid precursor protein (APP)—whether ligand or receptor—have not yet been found is that one of its major partners ...